From Latin transmutationem (nom. transmutatio) "a change, shift," noun of action from Latin transmutare "change from one condition to another," from trans- "thoroughly" (see trans-) + mutare "to change." To change from one substance or form to another. A term from alchemy, whose entire science is focused on the change of the impure into the pure.
"No one can Self-realize without transmutation." - Samael Aun Weor, Tarot and Kabbalah